|
T9723 |
GluR6 antagonist-1
|
|
Src
|
|
GluR6 antagonist-1 inhibits the pY binding site of tyrosine kinase p56lck SH2 domain. |
|
TQ0046 |
Bavisant
|
JNJ-31001074 |
Histamine Receptor
|
|
Bavisant (JNJ-31001074) is a selective and orally active Human H3 receptor antagonist. Bavisant can be used in research on mechanisms of action, involving wakefulness and cognition and the treatment for ADHD. |
|
T8944 |
TTA-A2
|
|
Calcium Channel
|
|
TTA-A2 is a selective T-type calcium channel antagonist as a potent anticonvulsant that the Cav3.1 isoform plays a prominent role in mediating. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels ... |
|
T8930 |
CID44216842
|
KUC103479N-02 |
CDK
,
Ras
|
|
CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT... |
|
T6950 |
PNU-120596
|
NSC 216666 |
AChR
|
|
PNU-120596 (NSC-216666) is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM. |
|
T15247 |
ESI-05
|
NSC 116966 |
cAMP
|
|
ESI-05 (NSC-116966) is a specific EPAC2 (exchange protein directly activated by cAMP 2) antagonist (IC50: 0.4 μM). ESI-05 inhibits cAMP-mediated activation of EPAC2, as well as EAPC2, mediated Rap1 activation. |
|
T27838 |
Lirequinil
|
RO413696,RO-413696,RO41-3696,RO 413696,Ro 41-3696,Ro-41-3696 |
GABA Receptor
|
|
Lirequinil (Ro 41-3696) is a small molecule GABAA receptor agonist used to study neurological disorders. |
|
T24840 |
STS-E412
|
STS E412,STSE412 |
Others
|
|
STS-E412 is a tissue-protective and selective EPOR/CD131 receptor activator for the study of neurological disorders. |
|
T68063 |
Elopiprazole
|
DU 29840 |
Others
|
|
Elopiprazole(DU 29840) is an anti-neurological compound that can be used to study neurological disorders. |
|
T11278 |
FG8119
|
NNC13-8119 |
Others
|
|
FG8119 is a novel benzodiazepine agonist with potential anticonvulsant and antiepileptic activity for the study of neurological disorders. |
|
T15655 |
KFM19
|
|
Adenosine Receptor
|
|
KFM19 is a potent and selective adenosine receptor (A1-receptor) antagonist (IC50 : 50 nM) for the study of neurological disorders. |
|
T10056 |
Neurokinin antagonist 1
|
|
Neuropeptide Y Receptor
|
|
Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders. |
|
T28258 |
Org-13011 fumarate
|
Org13011,Org 13011 |
5-HT Receptor
|
|
Org-13011 fumarate1 is an agonist of the 5-HT1A receptor and can be used to study neurological disorders. |
|
T28441 |
PPI-1019
|
PPI1019,Apan |
Beta Amyloid
|
|
PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD). |
|
T27143 |
Delucemine Hydrochloride
|
NPS 1506,Delucemine,Delucemine HCl,NPS1506,NPS-1506 |
NMDAR
|
|
Delucemine Hydrochloride (Delucemine) is a polyamine NMDA receptor antagonist used in the study of neurological disorders such as depression and Alzheimer's disease. |
|
T26085 |
Rilapine
|
Rilapinum |
5-HT Receptor
|
|
Rilapine (Rilapinum) is an antipsychotic compound that shows high affinity for 5-HT6 receptors and can be used to study neurological disorders. |
|
T27572 |
Ibuprofen diethylaminoethyl ester
|
Brufen diethylaminoethyl ester,BF-DEAE,BF DEAE |
Others
|
|
Ibuprofen diethylaminoethyl ester (BF DEAE) has anti-inflammatory activity, acts as a local anaesthetic and can be used in the study of neurological disorders. |
|
T15023 |
CX-157
|
KP 157 |
MAO
|
|
CX-157 (KP 157) is a novel monoamine oxidase-A (MAO-A) inhibitor for the study of depression-like neurological disorders and cancer. |
|
T11424 |
Glutaminyl Cyclase Inhibitor 1
|
|
Guanylate cyclase
|
|
Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor (IC50: 0.5 μM) that can be used to study neurological disorders. |
|
T22638 |
CBiPES hydrochloride
|
CBiPES HCl |
GluR
|
|
CBiPES hydrochloride (CBiPES HCl) is a potent orthosteric modulator of the mGlu2 receptor with an EC50 value of 92.8 nM.CBiPES hydrochloride blocks the action of WT and mGlu(3) receptors.CBiPES hydrochloride can be used ... |
|
T67954 |
Endixaprine
|
SR 41378 |
|
|
Endixaprine (SR 41378) is a small molecule compound used to treat neurological disorders and may be used to study anxiety disorders and epilepsy. |
|
T68035 |
Capeserod
|
SL-650155,SL-65.0155 |
5-HT Receptor
|
|
Capeserod is a potential 5-HT4 receptor (5-hydroxytryptamine receptor 4) agonist for the study of digestive disorders and neurological disorders. |
|
T14974 |
Citenamide
|
Cytenamide,AY-15613 |
Others
|
|
Citenamide (AY-15613) has anticancer and anticonvulsant activity and is used in the study of neurological disorders because of its sleep-promoting properties. |
|
T31354 |
Decimemide
|
V 285,V-285,V285 |
Others
|
|
Decimemide (V-285) is an alkoxybenzoic acid derivative with antiepileptic activity and potential anticonvulsant activity that can be used to study neurological disorders. |
|
T68093 |
Lobuprofen
|
|
COX
|
|
Lobuprofen is a small molecule COX inhibitor that is used to treat neurological disorders. |
|
T29663 |
ADL-5747
|
ADL-5747 (free base),ADL5747,ADL-5747 free base |
Opioid Receptor
|
|
ADL-5747 (ADL-5747 (free base)) (free base) is a delta opioid receptor agonist used in the treatment of neurological disorders, skin and musculoskeletal disorders, and may be used in the study of postherpetic neuralgia, ... |
|
T23973 |
DDD100097
|
DDD 100097,DDD-100097 |
Others
|
|
DDD100097 is a potent N-myristoyltransferase inhibitor with potential inhibitory effects on Trypanosoma brucei, which can be used to study neurological disorders. |
|
T68126 |
Pemedolac
|
Dexpemedolac |
COX
|
|
Pemedolac (Dexpemedolac) is a small molecule COX inhibitor used to treat neurological disorders, skin and musculoskeletal disorders. |
|
T31079 |
CP-810123
|
CP 810123,UNII-E6G4550EC4,CP810123 |
AChR
|
|
CP-810123 is a new alpha 7 nAChR agonist for the treatment of cognitive impairment associated with psychiatric or neurological disorders such as schizophrenia and Alzheimer's disease. |
|
T15816 |
LY341495
|
|
GluR
|
|
LY341495 is a potent metabotropic glutamate receptor antagonist that exhibits high activity against a wide range of glutamate receptor subtypes and can be used for the study of neurological disorders. |
|
T36707 |
ML 315
|
|
DYRK
,
CDK
|
|
ML 315 is a selective Clk and DYRK inhibitor with potential anticancer activity for the study of neurological disorders. |
|
T31750 |
Faxeladol
|
EM906,GCR 9905,EM 906,GCR-9905,EM-906,GCR9905 |
5-HT Receptor
,
Opioid Receptor
,
Adrenergic Receptor
|
|
Faxeladol, a potent adrenergic absorption inhibitor and serotonin reuptake inhibitor, is a small-molecule Opioid receptor agonist that can be used to study neurological disorders. |
|
T37429 |
TRPV3 antagonist 74a
|
TRPV3 74a |
TRP/TRPV Channel
|
|
TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders. |
|
T27257 |
EMD-503982
|
EMD503982,EMD 503982 |
Factor Xa
|
|
EMD-503982 is a potential Factor Xa and Factor VIIa inhibitor with potential anticancer and antitumor activity for the study of thromboembolic and neurological disorders. |
|
T23072 |
NNC 05-2090 hydrochloride
|
|
Transaminase
|
|
NNC 05-2090 hydrochloride is a betaine/GABA transporter (BGT-1) inhibitor with an IC50 value of 10.6 μM.NNC 05-2090 hydrochloride can be used for the study of epilepsy and neurological disorders. |
|
T28809 |
SLV-310
|
SLV 310,SLV310 |
Dopamine Receptor
,
5-HT Receptor
|
|
SLV-310 is a potent dopamine D2 receptor antagonist and 5-HT reuptake receptor inhibitor used in the study of neurological disorders such as bipolar disorder and schizophrenia. |
|
T31860 |
Fosdevirine
|
GSK-2248761A,IDX 899,GSK 2248761A,GSK 2248761,GSK-2248761,IDX-12899,GSK2248761,FDV,GSK2248761A |
HIV Protease
|
|
Fosdevirine (GSK2248761) is a selective and potent non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity for the study of neurological related disorders such as late-onset epilepsy. |
|
T28950 |
Terlakiren
|
CP 80794,CP-80,794 |
RAAS
|
|
Terlakiren (CP-80,794) is an orally active and potent renin inhibitor that inhibits the potency of human renin for the study of neurological disorders of the hypertension class. |
|
T11949 |
Masupirdine mesylate
|
SUVN-502 mesylate,SVN-502 mesylate |
5-HT Receptor
|
|
Masupirdine mesylate (SUVN-502 mesylate) is a selective 5-HT6 receptor antagonist that crosses the blood-brain barrier.Masupirdine mesylate is used in the study of neurological disorders such as Alzheimer's disease and d... |
|
T68084 |
Icopezil
|
|
AChE
|
|
Icopezil is a small molecule acetylcholinesterase in (AChE) inhibitor for the treatment of neurological disorders and can be used in the study of Alzheimer's disease. |
|
T77693 |
Nav1.8-IN-4
|
|
Sodium Channel
|
|
Nav1.8-IN-4 is a potent Nav1.8 channel inhibitor with potential analgesic activity.Nav1.8-IN-4 can be used for pain and neurological related disorders. |
|
T27830L |
Lifarizine FA
|
Lifarizine FA(119514-66-8 Free base) |
Sodium Channel
|
|
Lifarizine FA is a sodium channel blocker used in the treatment of neurological disorders and cardiovascular diseases, study of stroke. |
|
T27060 |
CP-226269
|
CP 226269,CP226269 |
Dopamine Receptor
|
|
CP-226269 is a potent dopamine D4 receptor agonist that regulates calcium flux and has an EC50 value of 32.0 nM. CP 226269 can be used to study neurological disorders such as schizophrenia. |
|
T77092 |
Nadecnemab
|
REGN-5069 |
Others
|
|
Nadecnemab is an IGG4-κantibody targeting GFRA3, a receptor of the glial cell-derived neurotrophic factor family. Nadecnemab can be used for knee osteoarthritis and neurological disorders. |
|
T24885 |
Tiospirone
|
BMY 13859-1 |
Dopamine Receptor
,
5-HT Receptor
|
|
Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and dopamine blocker that inhibits D2, 5-HT1a, 5-HT7, and sigma receptors.Tiospirone is used in the study of neurological disorders such as schizophrenia. |
|
T32368 |
KB-74935
|
KB 74935 |
Others
|
|
KB-74935 is an enzyme inhibitor and a mineralocorticoid receptor antagonist used to treat cholesterol, hypolipidemia, neurological disorders, and Alzheimer's disease. |
|
T26627L |
Anatibant 2HCl
|
Anatibant 2HCl(209733-45-9 Free base) |
Bradykinin Receptor
|
|
Anatibant 2HCl is a small molecule bradykinin B2 receptor antagonist for the treatment of neurological disorders and may be used in the study of brain injury. |
|
T13419 |
ROCK-IN-1
|
|
ROCK
|
|
ROCK-IN-1 is a potent ROCK inhibitor that inhibits ROCK2-mediated signaling with an IC50 value of 1.2 nM.ROCK-IN-1 can be used in the study of neurological disorders and inflammation-related diseases. |
|
T23335 |
SCH 221510
|
SCH-221510,SCH221510 |
Opioid Receptor
|
|
SCH 221510 is an orally available, selective and potent NOP agonist with an EC50 of 12 nM and a Ki of 0.3 nM.SCH 221510 has anxiolytic activity and can be used to study neurological disorders. |
|
T38732 |
PERK-IN-4
|
|
PERK
|
|
PERK-IN-4 is a potent and selective PERK inhibitor with an IC50 value of 0.3 nM.PERK-IN-4 can be used in the study of cancer and neurological disorders. |
